Finasteride, alopecia and side effects: everything you need to know

Finasteride is a medication widely used to treat androgenetic alopecia (male pattern baldness). Although it is effective for many patients, it is important to understand its potential consequences and the risks associated with its long-term use.

Finasteride is an inhibitor of 5α-reductase type 2, an enzyme present in the hair follicles of the scalp. Its main action is to block the transformation of testosterone into dihydrotestosterone (DHT), an androgen responsible for the miniaturization of hair follicles in men suffering from androgenetic alopecia.

Finasteride is an inhibitor of 5α-reductase type 2, an enzyme present in the hair follicles of the scalp. Its main action is to block the transformation of testosterone into dihydrotestosterone (DHT), an androgen responsible for the miniaturization of hair follicles in men suffering from androgenetic alopecia.

By reducing DHT levels in the scalp, this treatment can slow the progression of hair loss and, in some cases, promote regrowth. In addition, some users opt for hair growth gummies or hair supplements to provide nutritional support to the follicles and optimize results.

This treatment is prescribed to treat early stages of androgenetic alopecia in men aged 18 to 41. It is particularly effective in stabilizing hair loss and can even stimulate regrowth in some cases. Doctors generally recommend it when topical treatments, such as minoxidil, have not given satisfactory results or as a first-line treatment for certain patients.

Finasteride was originally developed to treat benign prostatic hyperplasia. Its effectiveness in treating alopecia was later discovered, leading to its approval for this indication. In 1997, the US Food and Drug Administration (FDA) approved the use of finasteride 1 mg for the treatment of male androgenetic alopecia. Since then, it has become one of the most prescribed treatments for this condition.

This medication, although effective in treating hair loss due to androgenetic alopecia (baldness), is associated with various side effects that can affect the quality of life of those treated. These effects, some of which mainly concern sexual and psychological aspects, must be taken into account before starting treatment and deserve careful reading to understand their potential impact. Similarly, patients who have tried alternative treatments such as minoxidil should also learn about the side effects of minoxidil to assess the best therapeutic choice.

This medication, although effective in treating hair loss due to androgenetic alopecia (baldness), is associated with various side effects that can affect the quality of life of those treated. These effects, some of which mainly concern sexual and psychological aspects, must be taken into account before starting treatment and deserve careful reading to understand their potential impact. Similarly, patients who have tried alternative treatments such as minoxidil should also learn about the side effects of minoxidil to assess the best therapeutic choice.

Psychological side effects are among the most common and concerning for individuals taking this treatment. Associated psychological disorders include:

• Depression and anxiety : Mood changes, including depressed mood, have been reported in some patients taking this active ingredient.

• Suicidal thoughts : Although rare, some suicidal thoughts have been reported, requiring immediate medical attention.

These psychological disturbances can occur during or after treatment with finasteride. It is crucial for consumers to monitor any mood changes and consult a healthcare professional if necessary.

Finasteride may also impact sexual health; symptoms include:

• Decreased libido : Many users report a decrease in their sexual desire while taking finasteride.

• Erectile dysfunction : This problem is characterized by difficulty in achieving or maintaining an erection sufficient for satisfactory sexual intercourse. It has been observed that these disorders may persist even after stopping the medication.

• Ejaculation problems : People treated may experience problems such as premature ejaculation or reduced volume of ejaculate.

• Disturbance of sexual sensation : Some men report decreased sensitivity of the penis and external genitalia, which can affect sexual pleasure and arousal.

These side effects are often reversible after stopping treatment, but there are cases where they persist, which is referred to as post-treatment syndrome.

In addition to sexual and psychological effects, finasteride may cause other adverse reactions:

• Gynecomastia : An abnormal increase in breast volume in men has been observed in approximately 4 to 5% of patients treated with a higher dose of finasteride.

• Testicular pain : Although less common, some people have reported pain in the testicles during treatment.

• Potential risk of male breast cancer : Isolated cases of male breast cancer have been reported in finasteride users, requiring careful monitoring.

Post-finasteride syndrome is a group of persistent symptoms that may include sexual, cognitive, and emotional disturbances after stopping finasteride treatment. Although rare, this syndrome is recognized by some medical associations and is the subject of ongoing research to better understand its mechanisms and find effective therapeutic solutions.

It is essential that consumers are fully informed of the disadvantages associated with finasteride before starting treatment. Open communication with a healthcare professional helps ensure proper follow-up and that any concerning side effects are addressed promptly.

Long-term use of this drug raises questions about its potential long-term effects.

Studies have shown that the treatment remains effective for at least 5 years of continuous treatment. After this period, the effectiveness may gradually decrease, but the medication usually continues to slow the progression of alopecia.

Finasteride may affect sperm quality in some men. Although these effects are usually reversible, men trying to conceive should discuss them with their doctor.

Some studies have suggested a potential link between long-term use of this product and an increased risk of cardiovascular problems. However, these results are inconclusive and require further research.

Managing the side effects of this drug requires a careful and personalized approach. Here are the main recommendations for dealing with these side effects:

It is essential to maintain constant dialogue with your doctor or pharmacist. Any adverse effects, even minor, must be reported promptly to allow for appropriate assessment and appropriate management. This communication allows the doctor to adjust treatment if necessary and to monitor the development of warning signs.

Patients should be alert to the appearance of any new symptoms or changes in their health status. Particular attention should be paid to sexual and psychological adverse reactions, which are the most frequently reported.

The ANSM recommends stopping treatment immediately and consulting a doctor if certain specific side effects appear. For example:

• If you experience mood changes, such as feelings of sadness, anxiety, tiredness, or difficulty concentrating.

• If signs of an allergic reaction occur, such as swelling of the lips, face, tongue or throat.

It is important to regularly reassess with your doctor the balance between the benefits of the medication and the potential risks. This assessment allows you to decide whether to continue, adjust or stop treatment.

For people experiencing psychological side effects, psychological support may be beneficial. It can help manage anxiety, depression, or other mood disturbances that may occur while taking the medication.

If side effects are severe or persistent, it may be worth considering alternatives to finasteride. Your doctor may suggest other treatment options for androgenetic alopecia.

Even after stopping treatment, medical monitoring is recommended. Some discomfort may persist after stopping the medication, a phenomenon sometimes called "post-finasteride syndrome".

It is crucial that people being treated are fully informed of the potential dangers before starting treatment and receive regular updates on this information. The ANSM even recommends a "reflection period" before starting finasteride. By following these recommendations and maintaining close communication with healthcare professionals, people being treated can better manage the potential adverse effects of finasteride and make informed decisions about their treatment.

For those who cannot or do not want to use finasteride, there are several alternatives.

• Minoxidil : Topical minoxidil is an effective medication for androgenetic alopecia. It stimulates growth and can be used alone or in combination with other treatments.

• Topical treatments: Topical solutions containing ingredients such as caffeine, procyanidin B2, or saw palmetto may provide benefit for some patients.

• Light therapies: Light treatments, such as low-level laser therapy, may stimulate hair growth in some individuals.

• Nutritional supplements: Certain supplements, such as biotin, zinc and iron, as well as specific dietary supplements , can help improve hair health, especially in people with deficiencies. It is recommended to consult your pharmacist to determine the most suitable supplements and ensure safe monitoring.

• Surgical Treatments: For more advanced cases, hair transplants can offer a permanent solution to hair loss.

• Natural approaches: Lifestyle changes, such as eating a balanced diet, managing stress and avoiding harsh hair treatments, can help maintain healthy hair.

Finasteride remains an effective treatment for androgenetic alopecia in many men. However, it is essential to carefully weigh the potential benefits against the risks of side effects. An informed decision regarding the use of the drug should be made in consultation with a healthcare professional, taking into account individual medical history, personal preferences, and available alternatives.

Research continues in the field of alopecia treatments, and new therapeutic options may emerge in the future, potentially offering a better balance between efficacy and safety.

Ultimately, management of androgenetic alopecia requires a personalized approach, taking into account not only the physical appearance, but also the patient's overall well-being and quality of life.

For any additional information, contact a health specialist.

This medication is used to treat androgenetic alopecia (male pattern baldness) and may actually help hair grow back. The expected effects usually appear between 3 and 6 months after starting the medication, and about 65% of people show improvement after one year of treatment. However, the effectiveness of finasteride varies among individuals, and results may fade after stopping the medication.

Treatment should be discontinued if serious adverse effects occur, including psychiatric disorders such as depression or suicidal ideation. Consumers are encouraged to consult their doctor before stopping treatment to discuss symptoms and potential risks. It is also advisable to stop the medication if persistent sexual side effects occur.

The most common side effects of treatment include sexual dysfunction such as decreased libido, erectile dysfunction, and ejaculation disorders. These effects are related to the mechanism of action of the drug which blocks the production of dihydrotestosterone (DHT). Although these effects are usually reversible when treatment is stopped, they may persist in some cases.

Taking this medication may be helpful for those who want to treat androgenetic alopecia, as it can slow hair loss and promote hair regrowth. However, due to its potential side effects, including on mental and sexual health, it is important to weigh the benefits against the harms before starting treatment. A medical consultation is recommended to assess whether finasteride is appropriate for each individual.